Mesoridazine is an orally active phenothiazine antipsychotic agent that primarily targets the human ether-a-go-go related gene (hERG) channels. It functions as a potent and rapid open-channel blocker, inhibiting hERG currents with an IC50 of 550 nM in human embryonic kidney 293 cells. Mesoridazine is utilized in research focused on schizophrenia and various other psychiatric disorders, making it a valuable reagent for studies in psychopharmacology.
Mesoridazine is an orally active phenothiazine antipsychotic agent that primarily targets the human ether-a-go-go related gene (hERG) channels. It functions as a potent and rapid open-channel blocker, inhibiting hERG currents with an IC50 of 550 nM in human embryonic kidney 293 cells. Mesoridazine is utilized in research focused on schizophrenia and various other psychiatric disorders, making it a valuable reagent for studies in psychopharmacology.
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