Fig. 1 · Structure
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Methazolamide
Carbonic Anhydrase Inhibitor
Methazolamide is an orally active inhibitor of carbonic anhydrase, demonstrating a Ki of 14 nM for human carbonic anhydrase II. This compound effectively reduces intraocular pressure and exhibits neuroprotective properties, including the ability to inhibit neuronal apoptosis. Methazolamide is applicable in research concerning ophthalmic diseases, such as glaucoma, and cerebrovascular conditions, including subarachnoid hemorrhage.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 554-57-4 |
| Applications | Carbonic Anhydrase Inhibitor |
| Formula | C5H8N4O3S2 |
| Molecular Weight | 236.27 |
| Synonyms | L584601 |
| SMILES | CC(/N=C1SC(S(=O)(N)=O)=NN/1C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.