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Biological Activity
Methyllycaconitine citrate is a potent antagonist for α7-containing neuronal nicotinic receptors (Ki = 1.4 nM). Interacts with α4β2 and α6β2 receptors at concentrations > 40 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 11.43 mL | 57.15 mL | 114.29 mL |
| 0.5 mM | 2.29 mL | 11.43 mL | 22.86 mL |
| 1 mM | 1.14 mL | 5.71 mL | 11.43 mL |
| 5 mM | 0.23 mL | 1.14 mL | 2.29 mL |
*The above data is based on the productmolecular weight 874.93. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12681 |
|---|---|
| CAS No. | 112825-05-5, 21019-30-7 |
| Formula | C37H50N2O10.C6H8O7 |
| M. Wt | 874.93 |
| Purity | >98% |
| SMILES | CCN1C[C@@]2(CC[C@@H]([C@@]34[C@@H]2[C@@H]([C@@](C31)([C@]5(C[C@@H]([C@H]6C[C@@H]4[C@@H]5[C@H]6OC)OC)O)O)OC)OC)COC(=O)C7=CC=CC=C7N8C(=O)C[C@@H](C8=O)C.C(C(=O)O)C(CC(=O)O)(C(=O)O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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