Methylpiperidino pyrazole (MPP) is a selective modulator of the estrogen receptor alpha (ERα). This compound demonstrates significant pro-apoptotic effects in endometrial cancer and oLE cell lines, counteracting the positive influence of beta-estradiol. Additionally, MPP exhibits mixed agonist and antagonist activity on murine uterine ERα in vivo, making it a valuable tool for research in estrogen signaling and related therapeutic applications.
Methylpiperidino pyrazole (MPP) is a selective modulator of the estrogen receptor alpha (ERα). This compound demonstrates significant pro-apoptotic effects in endometrial cancer and oLE cell lines, counteracting the positive influence of beta-estradiol. Additionally, MPP exhibits mixed agonist and antagonist activity on murine uterine ERα in vivo, making it a valuable tool for research in estrogen signaling and related therapeutic applications.
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