Biological Activity
Metixene hydrochloride hydrate is an anticholinergic antiparkinsonian agent, potently inhibits binding of quinuclidinyl benzilate (QNB) to the muscarinic receptor in rat brain cortical tissue, with an IC50 of 55 nM and a Kd of 15 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.48 mL | 137.39 mL | 274.77 mL |
0.5 mM | 5.5 mL | 27.48 mL | 54.95 mL |
1 mM | 2.75 mL | 13.74 mL | 27.48 mL |
5 mM | 0.55 mL | 2.75 mL | 5.5 mL |
*The above data is based on the productmolecular weight 363.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A18028 |
---|---|
M. Wt | 363.94 |
Formula | C20H26ClNOS |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 7081-40-5 |
SMILES | CN1CC(CCC1)CC2C3=C(C=CC=C3)SC4=C2C=CC=C4.Cl.O |
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