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Mifepristone (Mifeprex)

Catalog No.: A10591

Mifepristone (Mifeprex)

Mifepristone (Mifeprex) Chemical Structure

CAS NO. 84371-65-3

Mifepristone, an antioxidant and glucocorticoid receptor antagonist, demonstrates the ability to suppress activation of NFκB, a nuclear transcription factor that affects the expression of various adhesion molecules and several inflammatory genes.

Availability: In stock

Package Price Qty
25 mg
$30.00
50 mg
$40.00
100 mg
$50.00
250 mg
$85.00
10mM * 1mL in DMSO
$55.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Shuang Liang, .et al. Progesterone Changes the Pregnancy-Induced Adaptation of Cardiomyocyte Kv2.1 Channels via MicroRNA-29b, Cardiovasc Ther, 2022, Apr 7;2022:7145699 PMID: 35474714

Biological Activity

Mifepristone, an antioxidant and glucocorticoid receptor antagonist, demonstrates the ability to suppress activation of NFκB, a nuclear transcription factor that affects the expression of various adhesion molecules and several inflammatory genes.
Targets
Progesterone receptor Glucocorticoid receptor
0.2 nM2.6 nM
In vitro DMSO 77 mg/mL (179.24 mM)
Water Insoluble
Ethanol 17 mg/mL (39.57 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.28 mL 116.39 mL 232.77 mL
0.5 mM 4.66 mL 23.28 mL 46.55 mL
1 mM 2.33 mL 11.64 mL 23.28 mL
5 mM 0.47 mL 2.33 mL 4.66 mL

*The above data is based on the productmolecular weight 429.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10591
CAS No. 84371-65-3
Formula C29H35NO2
M. Wt 429.6
Purity >98%
Synonyms RU-486, Mifegyne
SMILES CC#C[[email protected]@]1(CC[[email protected]@H]2[[email protected]@]1(C[[email protected]@H](C3=C4CCC(=O)C=C4CC[[email protected]@H]23)C5=CC=C(C=C5)N(C)C)C)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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