Mirabegron

Catalog No.: A12861

β3 adrenergic receptor activator

Mirabegron

Mirabegron Chemical Structure

CAS NO. 223673-61-8

Mirabegron is a potent bladder relaxant and reagent for diabetes remedy.

Availability: In stock

Package Price Qty
5 mg
$80.00
10 mg
$140.00
25 mg
$280.00
50 mg
$450.00
10mM * 1mL in DMSO
$122.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Bhavik Patel, .et al. Combination drug therapy against OAB normalizes micturition parameters and increases the release of nitric oxide during chemically induced cystitis, Pharmacol Res Perspect, 2020, 8 (1), e00564 PMID: 32030913

Biological Activity

Mirabegron is a potent bladder relaxant and reagent for diabetes remedy.
Targets
β3-adrenoceptor
22.4 nM(EC50)
In vitro (25°C) DMSO 70 mg/mL (176.53 mM)
Water Insoluble
Ethanol 7 mg/mL (17.65 mM)
In vivo 2% DMSO+30% PEG 300+ddH2O 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.22 mL 126.1 mL 252.2 mL
0.5 mM 5.04 mL 25.22 mL 50.44 mL
1 mM 2.52 mL 12.61 mL 25.22 mL
5 mM 0.5 mL 2.52 mL 5.04 mL

*The above data is based on the productmolecular weight 396.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12861
Actions Activator
CAS No. 223673-61-8
Formula C21H24N4O2S
M. Wt 396.51
Purity >98%
SMILES C1=CC=C(C=C1)[[email protected]](CNCCC2=CC=C(C=C2)NC(=O)CC3=CSC(=N3)N)O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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