Catalog No.: A13467

PDE4 inhibitor


MK-0359 Chemical Structure

CAS NO. 346629-30-9

MK-0359 is a selective and potent oral PDE4 inhibitor, in chronic asthma.

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Biological Activity

MK-0359 is a selective and potent oral PDE4 inhibitor, in chronic asthma.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.01 mL 85.07 mL 170.15 mL
0.5 mM 3.4 mL 17.01 mL 34.03 mL
1 mM 1.7 mL 8.51 mL 17.01 mL
5 mM 0.34 mL 1.7 mL 3.4 mL

*The above data is based on the productmolecular weight 587.7181. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13467
Actions Inhibitor
CAS No. 346629-30-9
Formula C31H29N3O5S2
M. Wt 587.7181
Purity >98%
Synonyms L-454560, MK 0359, MK0359
SMILES CC1=NOC(=N1)C(=CC2=CC=CC(=C2)C3=C4C(=CC(=C3)C(C)(C)S(=O)(=O)C)C=CC=N4)C5=CC=C(C=C5)S(=O)(=O)C

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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