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$0.00 - MA Sartim, .et al. Crotoxin-Induced Mice Lung Impairment: Role of Nicotinic Acetylcholine Receptors and COX-Derived Prostanoids, Biomolecules, 2020, May; 10(5): 794 PMID: 32443924
Biological Activity
MK-0591 is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC50 value of 1.6 nM in a FLAP binding assay.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.03 mL | 85.15 mL | 170.31 mL |
| 0.5 mM | 3.41 mL | 17.03 mL | 34.06 mL |
| 1 mM | 1.7 mL | 8.52 mL | 17.03 mL |
| 5 mM | 0.34 mL | 1.7 mL | 3.41 mL |
*The above data is based on the productmolecular weight 587.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15163 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 136668-42-3 |
| Formula | C34H35ClN2O3S |
| M. Wt | 587.17 |
| Purity | >98% |
| Synonyms | Quiflapon, MK0591, MK 0591 |
| SMILES | CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)CC5=CC=C(C=C5)Cl)CC(C)(C)C(=O)O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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