MK-0591 (Quiflapon)

Catalog No.: A15163

FLAP inhibitor

MK-0591 (Quiflapon)

MK-0591 (Quiflapon) Chemical Structure

CAS NO. 136668-42-3

MK-0591 is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC50 value of 1.6 nM in a FLAP binding assay.

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Package Price Qty
10 mg
$110.00
50 mg
$670.00
200 mg
$1,700.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • MA Sartim, .et al. Crotoxin-Induced Mice Lung Impairment: Role of Nicotinic Acetylcholine Receptors and COX-Derived Prostanoids, Biomolecules, 2020, May; 10(5): 794 PMID: 32443924

Biological Activity

MK-0591 is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC50 value of 1.6 nM in a FLAP binding assay.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.03 mL 85.15 mL 170.31 mL
0.5 mM 3.41 mL 17.03 mL 34.06 mL
1 mM 1.7 mL 8.52 mL 17.03 mL
5 mM 0.34 mL 1.7 mL 3.41 mL

*The above data is based on the productmolecular weight 587.17. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15163
Actions Inhibitor
M. Wt 587.17
Formula C34H35ClN2O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 136668-42-3
Synonyms Quiflapon, MK0591, MK 0591
SMILES CC(C)(C)SC1=C(N(C2=C1C=C(C=C2)OCC3=NC4=CC=CC=C4C=C3)CC5=CC=C(C=C5)Cl)CC(C)(C)C(=O)O

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