Doravirine (MK-1439)

Catalog No.: A12443

NNRT inhibitor

Doravirine (MK-1439)

Doravirine (MK-1439) Chemical Structure

CAS NO. 1338225-97-0

MK-1439 is a non-nucleoside reverse transcriptase inhibitor

Availability: In stock

Package Price Qty
5 mg
$240.00
10 mg
$400.00
25 mg
$800.00
50 mg
$1,500.00
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Biological Activity

MK-1439 is a non-nucleoside reverse transcriptase inhibitor
In vitro DMSO 82 mg/mL (192.59 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.53 mL 117.63 mL 235.27 mL
0.5 mM 4.71 mL 23.53 mL 47.05 mL
1 mM 2.35 mL 11.76 mL 23.53 mL
5 mM 0.47 mL 2.35 mL 4.71 mL

*The above data is based on the productmolecular weight 425.05. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12443
Actions Inhibitor
CAS No. 1338225-97-0
Formula C17H11ClF3N5O3
M. Wt 425.05
Solubility DMSO
Purity >98%
Synonyms MK1439, MK 1439
SMILES CN1C(=NNC1=O)CN2C=CC(=C(C2=O)OC3=CC(=CC(=C3)C#N)Cl)C(F)(F)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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