MK-3102

Name: MK-3102
SKU: A13310
Price: 64.8 USD
Rating: 5 (288 reviews)

Catalog No.: A13310

DPP-4 inhibitor

Omarigliptin (MK-3102) is a competitive, reversible inhibitor of DPP-4 (IC50 = 1.6 nM, Ki = 0.8 nM). It is highly selective over all proteases tested (IC50 > 67 μM), including QPP, FAP, PEP, DPP8, and DPP9 and has weak ion channel activity (IC50 > 30 μM at IKr, Caγ1.2, and Naγ1.5).

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Grouped product items
Product Name	Price	Stock
MK-3102 5mg	Special Price $64.80 Regular Price $81.00	In stock
MK-3102 10mg	Special Price $110.40 Regular Price $138.00	In stock
MK-3102 25mg	Special Price $194.40 Regular Price $243.00	In stock
MK-3102 50mg	Special Price $324.00 Regular Price $405.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Biological Activity

Discription	Omarigliptin (MK-3102) is a competitive, reversible inhibitor of DPP-4 (IC50 = 1.6 nM, Ki = 0.8 nM). It is highly selective over all proteases tested (IC50 > 67 μM), including QPP, FAP, PEP, DPP8, and DPP9 and has weak ion channel activity (IC50 > 30 μM at IKr, Caγ1.2, and Naγ1.5).

Product Information

Catalog Num	A13310
Formula	C17H20F2N4O3S
Molecular Weight	398.43
CAS Number	1226781-44-7
SMILES	CS(=O)(=O)N1C=C2CN(CC2=N1)[C@@H]3C[C@@H]([C@H](OC3)C4=C(C=CC(=C4)F)F)N
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	77 mg/mL (193.25 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.1 mL	125.49 mL	250.99 mL
0.5 mM	5.02 mL	25.1 mL	50.2 mL
1 mM	2.51 mL	12.55 mL	25.1 mL
5 mM	0.5 mL	2.51 mL	5.02 mL

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