MK-4541

Catalog No.: A69132
Androgen Receptor Modulator
MK-4541 is a selective androgen receptor modulator (SARM) that functions primarily as an antagonist to inhibit 5α-reductase activity. This compound demonstrates potent anti-proliferative effects and induces apoptosis in androgen receptor-positive prostate cancer cells. In preclinical studies, MK-4541 significantly inhibited the growth of R3327-G prostate tumors in a xenograft mouse model, highlighting its potential for targeted prostate cancer therapy.
Grouped product items
Size Price Stock Qty
25mg
$1,405.00
In stock
50mg
$1,790.00
In stock
100mg
$2,240.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMK-4541 is a selective androgen receptor modulator (SARM) that functions primarily as an antagonist to inhibit 5α-reductase activity. This compound demonstrates potent anti-proliferative effects and induces apoptosis in androgen receptor-positive prostate cancer cells. In preclinical studies, MK-4541 significantly inhibited the growth of R3327-G prostate tumors in a xenograft mouse model, highlighting its potential for targeted prostate cancer therapy.
Product Information
Catalog NumA69132
FormulaC22H31F3N2O3
Molecular Weight428.49
CAS Number796885-38-6
SMILESC[C@@]12[C@]3([H])[C@](CC[C@@]1([H])N(C(C=C2)=O)C)([H])[C@@]4([H])[C@@](C)([C@@H](NC(OCC(F)(F)F)=O)CC4)CC3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2