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MK-8389

Catalog No.: A85306
FSH Receptor Agonist
MK-8389 is an orally active low molecular weight allosteric agonist of the follicle-stimulating hormone (FSH) receptor. This compound enhances FSH receptor signaling, impacting various physiological processes, including thyroid function regulation. MK-8389 is useful in research applications related to reproductive biology and endocrinology, providing insights into FSH receptor-mediated pathways.
MK-8389 1177015-12-1 FSH Receptor Agonist
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMK-8389 is an orally active low molecular weight allosteric agonist of the follicle-stimulating hormone (FSH) receptor. This compound enhances FSH receptor signaling, impacting various physiological processes, including thyroid function regulation. MK-8389 is useful in research applications related to reproductive biology and endocrinology, providing insights into FSH receptor-mediated pathways.
Product Information
Catalog NumA85306
FormulaC27H34N2O2S
Molecular Weight450.64
CAS Number1177015-12-1
SMILESO=C(N(C(C)(C)C)C)C1=CC(C2=CC=CS2)=C3C4=C(CCN13)C=C(OC)C(CC(C)C)=C4
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Endocrinology-Hormones > Estrogen Receptors