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Biological Activity
ML-161 is an inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets).
Targets
In vitro | DMSO | 68 mg/mL (188.24 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 27.68 mL | 138.42 mL | 276.83 mL |
0.5 mM | 5.54 mL | 27.68 mL | 55.37 mL |
1 mM | 2.77 mL | 13.84 mL | 27.68 mL |
5 mM | 0.55 mL | 2.77 mL | 5.54 mL |
*The above data is based on the productmolecular weight 361.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A13495 |
---|---|
Actions | Inhibitor |
CAS No. | 423735-93-7 |
Formula | C17H17BrN2O2 |
M. Wt | 361.23 |
Purity | >98% |
Synonyms | ML-161, ML161 |
SMILES | CCCC(=O)NC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2Br |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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