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ML 161

Catalog No.: A13495

PAR1 inhibitor

ML 161

ML 161 Chemical Structure

CAS NO. 423735-93-7

ML-161 is an inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets).

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
25 mg
$220.00
50 mg
$380.00
10mM * 1mL in DMSO
$102.00
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Biological Activity

ML-161 is an inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets).
Targets
In vitro DMSO 68 mg/mL (188.24 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.68 mL 138.42 mL 276.83 mL
0.5 mM 5.54 mL 27.68 mL 55.37 mL
1 mM 2.77 mL 13.84 mL 27.68 mL
5 mM 0.55 mL 2.77 mL 5.54 mL

*The above data is based on the productmolecular weight 361.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13495
Actions Inhibitor
CAS No. 423735-93-7
Formula C17H17BrN2O2
M. Wt 361.23
Purity >98%
Synonyms ML-161, ML161
SMILES CCCC(=O)NC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2Br
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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