ML 161

Catalog No.: A13495

PAR1 inhibitor

ML 161 Chemical Structure

CAS NO. 423735-93-7

ML-161 is an inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets).

Availability: In stock

Package Price Qty
5 mg
$60.00
10 mg
$100.00
25 mg
$220.00
50 mg
$380.00
10mM * 1mL in DMSO
$102.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ML-161 is an inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC50 = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets).
Targets
In vitro DMSO 72 mg/mL (199.31 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.68 mL 138.42 mL 276.83 mL
0.5 mM 5.54 mL 27.68 mL 55.37 mL
1 mM 2.77 mL 13.84 mL 27.68 mL
5 mM 0.55 mL 2.77 mL 5.54 mL

*The above data is based on the productmolecular weight 361.23. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13495
Actions Inhibitor
M. Wt 361.23
Formula C17H17BrN2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 423735-93-7
Synonyms ML-161, ML161
SMILES CCCC(=O)NC1=CC=CC(=C1)NC(=O)C2=CC=CC=C2Br

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