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Catalog No.: A17172

NRF2 inhibitor


ML-385 Chemical Structure

CAS NO. 846557-71-9

ML-385 is an inhibitor of nuclear factor erythroid 2-related factor 2 (Nrf2) with IC50 value of 1.9 μM.

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Biological Activity

ML-385 is an inhibitor of nuclear factor erythroid 2-related factor 2 (Nrf2) with IC50 value of 1.9 μM.
In vitro DMSO 68 mg/mL (132.91 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.55 mL 97.73 mL 195.47 mL
0.5 mM 3.91 mL 19.55 mL 39.09 mL
1 mM 1.95 mL 9.77 mL 19.55 mL
5 mM 0.39 mL 1.95 mL 3.91 mL

*The above data is based on the productmolecular weight 511.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A17172
Actions Inhibitor
CAS No. 846557-71-9
Formula C29H25N3O4S
M. Wt 511.6
Purity >98%
Synonyms ML385, ML 385

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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