ML-385
ML-385 is an inhibitor of nuclear factor erythroid 2-related factor 2 (Nrf2) with IC50 value of 1.9 μM.
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| Description | ML-385 is an inhibitor of nuclear factor erythroid 2-related factor 2 (Nrf2) with IC50 value of 1.9 μM. |
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| Catalog Num | A17172 |
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| Formula | C29H25N3O4S |
| Molecular Weight | 511.6 |
| CAS Number | 846557-71-9 |
| SMILES | O=C(NC1=NC(C2=CC=C(N(C(C3=CC=CC=C3C)=O)CC4)C4=C2)=C(C)S1)CC5=CC(OCO6)=C6C=C5 |
| Synonyms | ML385, ML 385 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 68 mg/mL (132.91 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| * <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. | |||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.55 mL | 97.73 mL | 195.47 mL |
| 0.5 mM | 3.91 mL | 19.55 mL | 39.09 mL |
| 1 mM | 1.95 mL | 9.77 mL | 19.55 mL |
| 5 mM | 0.39 mL | 1.95 mL | 3.91 mL |
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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
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