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- Praneeth Siripurapu, .et al. Two independent but synchronized Gβγ subunit-controlled pathways are essential for trailing-edge retraction during macrophage migration, J Biol Chem, 2017, Oct 20; 292(42): 17482-17495 PMID: 28864771
Biological Activity
ML 7 hydrochloride is a selective inhibitor of myosin light chain kinase (MLCK).
Targets
| In vitro | DMSO | 77 mg/mL (170.07 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.09 mL | 110.45 mL | 220.9 mL |
| 0.5 mM | 4.42 mL | 22.09 mL | 44.18 mL |
| 1 mM | 2.21 mL | 11.04 mL | 22.09 mL |
| 5 mM | 0.44 mL | 2.21 mL | 4.42 mL |
*The above data is based on the productmolecular weight 452.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11936 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 110448-33-4 |
| Formula | C15H17IN2O2S.HCl |
| M. Wt | 452.7 |
| Purity | >98% |
| Synonyms | ML-7 HCl |
| SMILES | C1CNCCN(C1)S(=O)(=O)C2=CC=CC3=C2C=CC=C3I.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Datasheet
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