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ML277

Catalog No.: A21749

KCNQ1 potassium channel activator

ML277

ML277 Chemical Structure

CAS NO. 1401242-74-7

ML277(CID53347902) is a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator with EC50 of 270 nM.

Availability: In stock

Package Price Qty
5 mg
$85.00
10 mg
$146.00
50 mg
$432.00
100 mg
$865.00
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Biological Activity

ML277(CID53347902) is a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator with EC50 of 270 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.2 mL 106.02 mL 212.05 mL
0.5 mM 4.24 mL 21.2 mL 42.41 mL
1 mM 2.12 mL 10.6 mL 21.2 mL
5 mM 0.42 mL 2.12 mL 4.24 mL

*The above data is based on the productmolecular weight 471.59. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21749
Actions Activator
CAS No. 1401242-74-7
Formula C23H25N3O4S2
M. Wt 471.59
Purity >98%
Synonyms ML-277, ML 277; CID-53347902, CID53347902, CID 53347902
SMILES O=C([[email protected]@H]1N(S(=O)(C2=CC=C(C)C=C2)=O)CCCC1)NC3=NC(C4=CC=C(OC)C=C4)=CS3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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