ML335

Catalog No.: A16957
TREK-1/2 Activator
ML335 is a potent and selective TREK-1/2 Activator. ML335 is an agonist for OPRM1-OPRD1 heterdimerization with an EC50 of 403 nM, and selectivities vs. OPRM1, OPRD1, and HTR5A of 37, 2.7, and >99, respectively.
Grouped product items
Product Name Price Stock Qty
ML335 5mg
$65.00
In stock
ML335 10mg
$110.00
In stock
ML335 50mg
$400.00
In stock
ML335 100mg
$700.00
In stock
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Biological Activity
Discription ML335 is a potent and selective TREK-1/2 Activator. ML335 is an agonist for OPRM1-OPRD1 heterdimerization with an EC50 of 403 nM, and selectivities vs. OPRM1, OPRD1, and HTR5A of 37, 2.7, and >99, respectively.
Product Information
Catalog Num A16957
Formula C15H14Cl2N2O3S
Molecular Weight 373.24
CAS Number 825658-06-8
SMILES O=C(NCC1=CC=C(Cl)C=C1Cl)C2=CC=C(NS(=O)(C)=O)C=C2
Synonyms ML-335, ML 335
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 74 mg/mL (198.25 mM)
Water Insoluble
Ethanol 5 mg/mL (13.39 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.79 mL 133.96 mL 267.92 mL
0.5 mM 5.36 mL 26.79 mL 53.58 mL
1 mM 2.68 mL 13.4 mL 26.79 mL
5 mM 0.54 mL 2.68 mL 5.36 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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