ML348

Catalog No.: A16338

LYPLA1 inhibitor

ML348

ML348 Chemical Structure

CAS NO. 899713-86-1

ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM), Exhibits 14-fold selectivity for LYPLA1 over LYPLA2, Also selective over a panel of ~30 other serine hydrolases.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$90.00
50 mg
$270.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM), Exhibits 14-fold selectivity for LYPLA1 over LYPLA2, Also selective over a panel of ~30 other serine hydrolases.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.05 mL 120.25 mL 240.51 mL
0.5 mM 4.81 mL 24.05 mL 48.1 mL
1 mM 2.41 mL 12.03 mL 24.05 mL
5 mM 0.48 mL 2.41 mL 4.81 mL

*The above data is based on the productmolecular weight 415.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16338
Actions Inhibitor
M. Wt 415.79
Formula C18H17ClF3N3O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 899713-86-1
Synonyms ML-348, ML 348
SMILES ClC1=C(NC(CN2CCN(C(C3=CC=CO3)=O)CC2)=O)C=C(C(F)(F)F)C=C1

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