ML367

Catalog No.: A18622

ATAD5 inhibitor

ML367

ML367 Chemical Structure

CAS NO. 381168-77-0

ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization, acts as a probe molecule that has low micromolar inhibitory activity. ML367 blocks DNA repair pathways, suppresses general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation.

Availability: In stock

Package Price Qty
5 mg
$400.00
10 mg
$700.00
50 mg
$2,100.00
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Biological Activity

ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization, acts as a probe molecule that has low micromolar inhibitory activity. ML367 blocks DNA repair pathways, suppresses general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.91 mL 149.56 mL 299.11 mL
0.5 mM 5.98 mL 29.91 mL 59.82 mL
1 mM 2.99 mL 14.96 mL 29.91 mL
5 mM 0.6 mL 2.99 mL 5.98 mL

*The above data is based on the productmolecular weight 334.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18622
Actions Inhibitor
M. Wt 334.32
Formula C19H12F2N4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 381168-77-0
Synonyms ML-367, ML 367
SMILES FC1=CC(NC2=NC(C3=CC=NC=C3)=NC4=CC=CC=C42)=CC=C1F

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