MM-151 is a humanized IgG1 monoclonal antibody that specifically targets the epidermal growth factor receptor (EGFR). By binding to multiple regions of the EGFR extracellular domain, MM-151 effectively inhibits EGFR signaling and cell proliferation while reducing mutations in circulating cell-free tumor DNA associated with EGFR resistance. This reagent is valuable for research into drug-resistant cancers, including colorectal cancer, non-small cell lung cancer, and triple-negative breast cancer.
MM-151 is a humanized IgG1 monoclonal antibody that specifically targets the epidermal growth factor receptor (EGFR). By binding to multiple regions of the EGFR extracellular domain, MM-151 effectively inhibits EGFR signaling and cell proliferation while reducing mutations in circulating cell-free tumor DNA associated with EGFR resistance. This reagent is valuable for research into drug-resistant cancers, including colorectal cancer, non-small cell lung cancer, and triple-negative breast cancer.
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