MM11253

Name: MM11253
Brand: Adooq Bioscience
SKU: A77456
Rating: 5 (288 reviews)

Catalog No.: A77456

RARγ Antagonist

MM11253 is a potent and selective antagonist of Retinoic Acid Receptor gamma (RARγ) with an IC50 of 44 nM. It exhibits minimal activity against RARα, RARβ, and RXRα. This compound effectively inhibits the growth-promoting effects of RARγ-selective agonists, making it a valuable tool for research focused on cancer biology and metabolism involving RARγ signaling pathways.

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Grouped product items
Size	Price	Stock
1mg	$25.00	In stock
5mg	$65.00	In stock
10mg	$110.00	In stock
25mg	$245.00	In stock
50mg	$375.00	In stock
100mg	$540.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	MM11253 is a potent and selective antagonist of Retinoic Acid Receptor gamma (RARγ) with an IC50 of 44 nM. It exhibits minimal activity against RARα, RARβ, and RXRα. This compound effectively inhibits the growth-promoting effects of RARγ-selective agonists, making it a valuable tool for research focused on cancer biology and metabolism involving RARγ signaling pathways.

Product Information

Catalog Num	A77456
Formula	C28H30O2S2
Molecular Weight	462.67
CAS Number	345952-44-5
SMILES	O=C(C1=CC=C2C=C(C3(C4=CC=C5C(C)(C)CCC(C)(C)C5=C4)SCCS3)C=CC2=C1)O

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