MNI-444

Catalog No.: A58057
A2AR Ligand
MNI-444 is a blood-brain barrier-permeable ligand for the adenosine A2A receptor (A2AR). This compound serves as a valuable tool in the investigation of non-dopaminergic pathways relevant to Parkinson's disease research. Its ability to selectively interact with A2AR positions it as a promising candidate for studying therapeutic strategies targeting neurodegenerative disorders.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMNI-444 is a blood-brain barrier-permeable ligand for the adenosine A2A receptor (A2AR). This compound serves as a valuable tool in the investigation of non-dopaminergic pathways relevant to Parkinson's disease research. Its ability to selectively interact with A2AR positions it as a promising candidate for studying therapeutic strategies targeting neurodegenerative disorders.
Product Information
Catalog NumA58057
FormulaC24H26FN9O2
Molecular Weight491.52
CAS Number1974301-94-4
SMILESNC1=NC(N(CCN2CCN(C3=CC=C(OCCF)C=C3)CC2)N=C4)=C4C5=NC(C6=CC=CO6)=NN15
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