MOR modulator-1 is a potent and selective modulator of the μ opioid receptor (MOR). This compound demonstrates enhanced receptor selectivity and improved antagonistic effects in vivo, resulting in fewer withdrawal symptoms compared to traditional opioids like NAT. With binding affinities (Kis) of 0.25 nM for MOR, 41.1 nM for δ, and 1.30 nM for γ receptors, MOR modulator-1 is a valuable tool for research in pain management and opioid receptor pharmacology.
MOR modulator-1 is a potent and selective modulator of the μ opioid receptor (MOR). This compound demonstrates enhanced receptor selectivity and improved antagonistic effects in vivo, resulting in fewer withdrawal symptoms compared to traditional opioids like NAT. With binding affinities (Kis) of 0.25 nM for MOR, 41.1 nM for δ, and 1.30 nM for γ receptors, MOR modulator-1 is a valuable tool for research in pain management and opioid receptor pharmacology.
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