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mP6

Catalog No.: A57494
Integrin β(3) Inhibitor
mP6 (Myr-FEEERA-OH) is an integrin β3 inhibitor that specifically targets the interaction between Gα13 and integrin β3, preserving talin-dependent integrin function. This myristoylated peptide effectively blocks GTP usage in Rac1, Rap1, and Rab7, thereby inhibiting the infection process in CHO-A24 cells. mP6 is valuable for research applications involving integrin signaling and modulation of cell adhesion pathways.
mP6 2700321-79-3 Integrin β(3) Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionmP6 (Myr-FEEERA-OH) is an integrin β3 inhibitor that specifically targets the interaction between Gα13 and integrin β3, preserving talin-dependent integrin function. This myristoylated peptide effectively blocks GTP usage in Rac1, Rap1, and Rab7, thereby inhibiting the infection process in CHO-A24 cells. mP6 is valuable for research applications involving integrin signaling and modulation of cell adhesion pathways.
Product Information
Catalog NumA57494
FormulaC47H75N9O14
Molecular Weight990.15
CAS Number2700321-79-3
Sequence{Myr}-Phe-Glu-Glu-Glu-Arg-Ala
Sequence shortening{Myr}-FEEERA
SMILES[C@H](CC1=CC=CC=C1)(C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(=N)N)C(N[C@H](C(O)=O)C)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)NC(CCCCCCCCCCCCC)=O
SynonymsMyr-FEEERA-OH
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Cytoskeleton > Integrin