MPEP HCl

Catalog No.: A13236

mGlu5 receptor antagonist

MPEP HCl

MPEP HCl Chemical Structure

CAS NO. 219911-35-0

MPEP is a potent, highly selective non-competitive antagonist at the mGlu5a receptor subtype (IC50 = 36 nM) while having no agonist or antagonist activities at the mGlu1b receptor at concentrations up to 30 uM.

Availability: In stock

Package Price Qty
25 mg
$120.00
50 mg
$200.00
100 mg
$350.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

MPEP is a potent, highly selective non-competitive antagonist at the mGlu5a receptor subtype (IC50 = 36 nM) while having no agonist or antagonist activities at the mGlu1b receptor at concentrations up to 30 uM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 43.54 mL 217.68 mL 435.35 mL
0.5 mM 8.71 mL 43.54 mL 87.07 mL
1 mM 4.35 mL 21.77 mL 43.54 mL
5 mM 0.87 mL 4.35 mL 8.71 mL

*The above data is based on the productmolecular weight 229.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A13236
Actions Antagonist
M. Wt 229.7
Formula C14H11N.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 219911-35-0
Synonyms MPEP hydrochloride
SMILES CC1=CC=CC(=N1)C#CC2=CC=CC=C2.Cl

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