MrgprX2 antagonist-3

Catalog No.: A61569
MrgprX2 Antagonist
MrgprX2 antagonist-3 is a selective antagonist of the Mas-related G protein-coupled receptor X2 (MrgprX2), primarily involved in mediating pruritic and inflammatory signaling. This compound exhibits significant efficacy in inhibiting MrgprX2-related pathways, making it a valuable tool for studying inflammatory skin disorders. Research applications include investigations into the role of MrgprX2 in various dermatological conditions and the development of novel therapeutic strategies targeting these pathways.
Grouped product items
Size Price Stock Qty
5mg
$115.00
In stock
10mg
$190.00
In stock
25mg
$380.00
In stock
50mg
$590.00
In stock
100mg
$920.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMrgprX2 antagonist-3 is a selective antagonist of the Mas-related G protein-coupled receptor X2 (MrgprX2), primarily involved in mediating pruritic and inflammatory signaling. This compound exhibits significant efficacy in inhibiting MrgprX2-related pathways, making it a valuable tool for studying inflammatory skin disorders. Research applications include investigations into the role of MrgprX2 in various dermatological conditions and the development of novel therapeutic strategies targeting these pathways.
Product Information
Catalog NumA61569
FormulaC16H20FN3O2S
Molecular Weight337.41
CAS Number2642174-19-2
SMILESC[C@H](O)CN(CC)C(NC1=NC=C(S1)CC2=CC(F)=CC=C2)=O
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