MRS-1191 is a selective antagonist of the A3 adenosine receptor, exhibiting a KB value of 92 nM and a Ki value of 31.4 nM for the human A3 receptor. This compound demonstrates an IC50 of 120 nM in CHO cells, making it an effective tool for investigating A3 receptor-related biological pathways. Additionally, MRS-1191 features an alkyne group, enabling its use as a click chemistry reagent through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
MRS-1191 is a selective antagonist of the A3 adenosine receptor, exhibiting a KB value of 92 nM and a Ki value of 31.4 nM for the human A3 receptor. This compound demonstrates an IC50 of 120 nM in CHO cells, making it an effective tool for investigating A3 receptor-related biological pathways. Additionally, MRS-1191 features an alkyne group, enabling its use as a click chemistry reagent through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules.
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