MRS5698

Catalog No.: A58017
A3AR Agonist
MRS5698 is a selective agonist of the A3 adenosine receptor (A3AR), effectively activating Gi protein signaling pathways. With Kis of approximately 3 nM for both human and mouse A3AR, this compound is valuable for investigating mechanisms related to pain and psoriasis. Its specificity may facilitate research into therapeutic applications targeting inflammatory and pain-related disorders.
Grouped product items
Size Price Stock Qty
1mg
$3,640.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMRS5698 is a selective agonist of the A3 adenosine receptor (A3AR), effectively activating Gi protein signaling pathways. With Kis of approximately 3 nM for both human and mouse A3AR, this compound is valuable for investigating mechanisms related to pain and psoriasis. Its specificity may facilitate research into therapeutic applications targeting inflammatory and pain-related disorders.
Product Information
Catalog NumA58017
FormulaC28H23ClF2N6O3
Molecular Weight564.97
CAS Number1377273-00-1
SMILESCNC([C@]12[C@]([C@](N3C4=NC(C#CC5=CC(F)=C(C=C5)F)=NC(NCC6=CC(Cl)=CC=C6)=C4N=C3)([H])[C@@H]([C@@H]2O)O)([H])C1)=O
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