MS436

Catalog No.: A13749

BRD4 inhibitor

MS436

MS436 Chemical Structure

CAS NO. 1395084-25-9

MS436 is a diazobenzene-based small-molecule inhibitor for the BRD4 bromodomains with a Ki value of 30-50 nM.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$125.00
25 mg
$250.00
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Biological Activity

MS436 is a diazobenzene-based small-molecule inhibitor for the BRD4 bromodomains with a Ki value of 30-50 nM.
Targets
BRD4 (1) BRD4 (2)
<0.085 μM(Ki)0.34 μM(Ki)
In vitro DMSO 50 mg/mL (130.4 mM)
Water Insoluble
Ethanol Warmed: 1 mg/mL (2.6 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.08 mL 130.41 mL 260.81 mL
0.5 mM 5.22 mL 26.08 mL 52.16 mL
1 mM 2.61 mL 13.04 mL 26.08 mL
5 mM 0.52 mL 2.61 mL 5.22 mL

*The above data is based on the productmolecular weight 383.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13749
Actions Inhibitor
CAS No. 1395084-25-9
Formula C18H17N5O3S
M. Wt 383.42
Solubility DMSO
Purity >98%
Synonyms MS 436, MS-436
SMILES CC1=C/C(=N/NC2=CC=C(C=C2)S(=O)(=O)NC3=CC=CC=N3)/C(=CC1=O)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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