MSX3

Catalog No.: A57939
Adenosine A2A Antagonist
MSX3 is a potent antagonist of the adenosine A2A receptor, demonstrating significant activity in modulating neuropharmacological responses. This compound has shown efficacy in reversing the effects of dopamine antagonism, specifically counteracting the impacts of Haloperidol on effort-related decision-making tasks in T-maze cost/benefit assessments. MSX3 is valuable for research exploring the roles of adenosine signaling in neurological disorders and the interplay between dopaminergic and adenosinergic systems.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMSX3 is a potent antagonist of the adenosine A2A receptor, demonstrating significant activity in modulating neuropharmacological responses. This compound has shown efficacy in reversing the effects of dopamine antagonism, specifically counteracting the impacts of Haloperidol on effort-related decision-making tasks in T-maze cost/benefit assessments. MSX3 is valuable for research exploring the roles of adenosine signaling in neurological disorders and the interplay between dopaminergic and adenosinergic systems.
Product Information
Catalog NumA57939
FormulaC21H21N4Na2O7P
Molecular Weight518.37
CAS Number261717-23-1
SMILESO=C(N1CC#C)N(CCCOP(O[Na])(O[Na])=O)C2=C(N(C)C(/C=C/C3=CC=CC(OC)=C3)=N2)C1=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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