Mu opioid receptor antagonist 9 is a selective antagonist of the mu-opioid receptor (MOR) with a Ki of 77.3 nM. This compound demonstrates high selectivity over kappa-opioid (KOR) and delta-opioid receptors (DOR), making it effective in reversing the antinociceptive effects associated with psychoactive substances. Additionally, Mu opioid receptor antagonist 9 has been shown to counteract respiratory depression induced by these substances in murine models. This reagent is valuable for research in Opioid Use Disorder (OUD).
Mu opioid receptor antagonist 9 is a selective antagonist of the mu-opioid receptor (MOR) with a Ki of 77.3 nM. This compound demonstrates high selectivity over kappa-opioid (KOR) and delta-opioid receptors (DOR), making it effective in reversing the antinociceptive effects associated with psychoactive substances. Additionally, Mu opioid receptor antagonist 9 has been shown to counteract respiratory depression induced by these substances in murine models. This reagent is valuable for research in Opioid Use Disorder (OUD).
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