Mutant IDH1-IN-4

Catalog No.: A19106

IDH1 inhibitor

Mutant IDH1-IN-4

Mutant IDH1-IN-4 Chemical Structure

CAS NO. 1416270-18-2

Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ?? 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells.

Availability: In stock

Package Price Qty
1 mg
$270.00
5 mg
$810.00
10 mg
$1,380.00
50 mg
$4,140.00
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Biological Activity

Mutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ?? 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.8 mL 114.01 mL 228.02 mL
0.5 mM 4.56 mL 22.8 mL 45.6 mL
1 mM 2.28 mL 11.4 mL 22.8 mL
5 mM 0.46 mL 2.28 mL 4.56 mL

*The above data is based on the productmolecular weight 438.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A19106
Actions Inhibitor
M. Wt 438.56
Formula C25H34N4O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1416270-18-2
SMILES N#CC1=C(N2C[[email protected]@H](C3CC3)N(C(CCOC)=O)CC2)N=C(C4CC4)C5=C1CC(C)(C)OC5

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