N-Arachidonylglycine-d8 is a deuterated analog of N-Arachidonylglycine, primarily functioning as a stable isotope. It acts as a selective agonist for the GPR18 receptor, with an EC50 of 44.5 nM, while showing no activity at CB1 or CB2 receptors. Additionally, N-Arachidonylglycine-d8 inhibits the glycine transporter GLYT2 with an IC50 of 5.1 μM and effectively promotes endometrial cell migration. This reagent is valuable in research exploring endocannabinoid signaling and transporter interactions.
N-Arachidonylglycine-d8 is a deuterated analog of N-Arachidonylglycine, primarily functioning as a stable isotope. It acts as a selective agonist for the GPR18 receptor, with an EC50 of 44.5 nM, while showing no activity at CB1 or CB2 receptors. Additionally, N-Arachidonylglycine-d8 inhibits the glycine transporter GLYT2 with an IC50 of 5.1 μM and effectively promotes endometrial cell migration. This reagent is valuable in research exploring endocannabinoid signaling and transporter interactions.
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