N-Cholyl-L-glutamic acid (GluCA) is a conjugate of cholic acid and L-glutamic acid, primarily targeting the pregnane X receptor (PXR). This compound is known to enhance the expression of PXR and induce the downstream target gene Cyp3a11. N-Cholyl-L-glutamic acid serves as a valuable tool in researching the mechanisms underlying Crohn's disease and other conditions related to altered PXR signaling.
N-Cholyl-L-glutamic acid (GluCA) is a conjugate of cholic acid and L-glutamic acid, primarily targeting the pregnane X receptor (PXR). This compound is known to enhance the expression of PXR and induce the downstream target gene Cyp3a11. N-Cholyl-L-glutamic acid serves as a valuable tool in researching the mechanisms underlying Crohn's disease and other conditions related to altered PXR signaling.
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