N-Deschlorobenzoyl indomethacin-d3 is a deuterium-labeled analog of N-Deschlorobenzoyl indomethacin, a primary metabolite of indomethacin that lacks the N-p-chlorobenzoyl group. This compound is utilized as a stable isotope in biomedical research, particularly for studies involving metabolic pathways and pharmacokinetics. Due to its structural modifications, N-Deschlorobenzoyl indomethacin-d3 exhibits diminished inhibitory activity against the enzymes AKR1C2 and AKR1C3, providing a useful reference for understanding drug metabolism and interactions in scientific investigations.
N-Deschlorobenzoyl indomethacin-d3 is a deuterium-labeled analog of N-Deschlorobenzoyl indomethacin, a primary metabolite of indomethacin that lacks the N-p-chlorobenzoyl group. This compound is utilized as a stable isotope in biomedical research, particularly for studies involving metabolic pathways and pharmacokinetics. Due to its structural modifications, N-Deschlorobenzoyl indomethacin-d3 exhibits diminished inhibitory activity against the enzymes AKR1C2 and AKR1C3, providing a useful reference for understanding drug metabolism and interactions in scientific investigations.
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