N-Desethyl-N-methyl vardenafil

Catalog No.: A42200
PDE5 Inhibitor
N-Desethyl-N-methyl vardenafil is a potent PDE5 inhibitor, exhibiting an IC50 value of 0.14 μM. This compound is primarily utilized in pharmacological research focused on the modulation of erectile dysfunction and related cardiovascular conditions. Its capacity to inhibit PDE5 facilitates increased levels of cyclic GMP, thus enhancing vascular smooth muscle relaxation and blood flow.
Grouped product items
Size Price Stock Qty
1mg
$40.00
In stock
5mg
$200.00
In stock
10mg
$410.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionN-Desethyl-N-methyl vardenafil is a potent PDE5 inhibitor, exhibiting an IC50 value of 0.14 μM. This compound is primarily utilized in pharmacological research focused on the modulation of erectile dysfunction and related cardiovascular conditions. Its capacity to inhibit PDE5 facilitates increased levels of cyclic GMP, thus enhancing vascular smooth muscle relaxation and blood flow.
Product Information
Catalog NumA42200
FormulaC22H30N6O4S
Molecular Weight474.58
CAS Number224785-87-9
SMILESCCOC(C=CC(S(N1CCN(CC1)C)(=O)=O)=C2)=C2C3=NC(C4=C(N=C(N4N3)CCC)C)=O
SynonymsDemethyl-vardenafil
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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