(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8)

Catalog No.: A62491
KOR Agonist
(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) functions as a potent kappa opioid receptor (KOR) agonist. This stable analog of Dynorphin A (1-8) exhibits significant biological activity in modulating pain and stress response pathways. Its application in research extends to studying opioid system dynamics and potential therapeutic strategies in pain management and neurobiology.
Grouped product items
Size Price Stock Qty
5mg
$350.00
In stock
10mg
$650.00
In stock
50mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) functions as a potent kappa opioid receptor (KOR) agonist. This stable analog of Dynorphin A (1-8) exhibits significant biological activity in modulating pain and stress response pathways. Its application in research extends to studying opioid system dynamics and potential therapeutic strategies in pain management and neurobiology.
Product Information
Catalog NumA62491
FormulaC50H81N15O9
Molecular Weight1036.27
CAS Number103613-84-9
Sequence{Tyr(Me)}-Gly-Gly-Phe-Leu-Arg-{Arg(N-Me)}-{d-Leu}-{NHEt}
Sequence shortening{Tyr(Me)}-GGFLR-{Arg(N-Me)}-{d-Leu}-{NHEt}
SMILESCCNC(=O)[C@@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)N(C)C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC
SynonymsE2078
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