N3-C2-NHS ester is a non-cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. Its robust reactivity makes it an essential tool in the development of targeted therapeutic agents in chemical and bioconjugation research.
N3-C2-NHS ester is a non-cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This compound features an azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules, as well as strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups. Its robust reactivity makes it an essential tool in the development of targeted therapeutic agents in chemical and bioconjugation research.
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