N3-C3-NHS ester is a non-cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This compound features an azide functionality, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified entities. N3-C3-NHS ester is a valuable tool for enhancing the specificity and efficacy of ADCs in targeted cancer therapies.
N3-C3-NHS ester is a non-cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs). This compound features an azide functionality, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAC) with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-modified entities. N3-C3-NHS ester is a valuable tool for enhancing the specificity and efficacy of ADCs in targeted cancer therapies.
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