N3-PEG2-C2-NHS ester is a non-cleavable 2-unit PEG linker designed for the synthesis of antibody-drug conjugates (ADCs). Featuring an azide functional group, it serves as a click chemistry reagent capable of facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, N3-PEG2-C2-NHS ester participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile tool for conjugation applications in bioconjugate chemistry.
N3-PEG2-C2-NHS ester is a non-cleavable 2-unit PEG linker designed for the synthesis of antibody-drug conjugates (ADCs). Featuring an azide functional group, it serves as a click chemistry reagent capable of facilitating copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, N3-PEG2-C2-NHS ester participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups, making it a versatile tool for conjugation applications in bioconjugate chemistry.
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