N3-PEG5-aldehyde is a cleavable linker designed for use in antibody-drug conjugates (ADCs), featuring a five-unit polyethylene glycol (PEG) structure. This compound contains an azide functional group, enabling its application in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of participating in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. N3-PEG5-aldehyde is valuable in the development of targeted therapeutics, enhancing drug delivery and efficacy.
N3-PEG5-aldehyde is a cleavable linker designed for use in antibody-drug conjugates (ADCs), featuring a five-unit polyethylene glycol (PEG) structure. This compound contains an azide functional group, enabling its application in click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it is capable of participating in strain-promoted azide-alkyne cycloaddition (SPAAC) reactions with dibenzocyclooctyne (DBCO) or bicyclononyne (BCN) groups. N3-PEG5-aldehyde is valuable in the development of targeted therapeutics, enhancing drug delivery and efficacy.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
