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Biological Activity
Naloxegol is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 13.48 mL | 67.4 mL | 134.8 mL |
| 0.5 mM | 2.7 mL | 13.48 mL | 26.96 mL |
| 1 mM | 1.35 mL | 6.74 mL | 13.48 mL |
| 5 mM | 0.27 mL | 1.35 mL | 2.7 mL |
*The above data is based on the productmolecular weight 741.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15972 |
|---|---|
| Actions | Antagonist |
| CAS No. | 1354744-91-4 |
| Formula | C36H55NO15 |
| M. Wt | 741.83 |
| Purity | >98% |
| Synonyms | NKTR118, AZ-13337019, EGylated naloxol |
| SMILES | O[[email protected]@]12CC[[email protected]](OCCOCCOCCOCCOCCOCCOCCOC)[[email protected]@]3([H])[[email protected]@]14CCN(CC=C)[[email protected]]2([H])CC5=C4C(O3)=C(O)C=C5.O=C(O)C(O)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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