Nampt-IN-10 is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), exhibiting nanomolar inhibitory activity in various cancer cell lines, including MDA-MB453, NCI-N87, and NCI-H526. This compound can be utilized as a payload in antibody-drug conjugates (ADCs), where it has been shown to enhance anti-tumor efficacy. It serves as a valuable tool for researchers investigating NAMPT's role in cancer metabolism and therapeutic resistance.
Nampt-IN-10 is a potent inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), exhibiting nanomolar inhibitory activity in various cancer cell lines, including MDA-MB453, NCI-N87, and NCI-H526. This compound can be utilized as a payload in antibody-drug conjugates (ADCs), where it has been shown to enhance anti-tumor efficacy. It serves as a valuable tool for researchers investigating NAMPT's role in cancer metabolism and therapeutic resistance.
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