NAT is a potent NAMPT activator, exhibiting an EC50 of 5.7 μM and a KD of 379 nM. As the rate-limiting enzyme in the NAD salvage pathway, NAMPT is crucial for maintaining cellular NAD levels, making it a valuable target for studying diseases linked to NAD depletion, such as neurodegenerative disorders. This compound is essential for research aiming to explore therapeutic strategies that enhance NAD metabolism and combat related pathologies.
NAT is a potent NAMPT activator, exhibiting an EC50 of 5.7 μM and a KD of 379 nM. As the rate-limiting enzyme in the NAD salvage pathway, NAMPT is crucial for maintaining cellular NAD levels, making it a valuable target for studying diseases linked to NAD depletion, such as neurodegenerative disorders. This compound is essential for research aiming to explore therapeutic strategies that enhance NAD metabolism and combat related pathologies.
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