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Biological Activity
Nav1.7-IN-3 is a selective, orally bioavailable voltage-gated sodium channel Nav1.7 inhibitor with an IC50 of 8 nM. Pain relief. Limited CNS penetration.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.2 mL | 116.02 mL | 232.05 mL |
| 0.5 mM | 4.64 mL | 23.2 mL | 46.41 mL |
| 1 mM | 2.32 mL | 11.6 mL | 23.2 mL |
| 5 mM | 0.46 mL | 2.32 mL | 4.64 mL |
*The above data is based on the productmolecular weight 430.95. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13626 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 1788872-06-9 |
| Formula | C17H20ClFN4O2S2 |
| M. Wt | 430.95 |
| Purity | >98% |
| SMILES | FC1=C(S(=O)(NC2=NC=CS2)=O)C=C(Cl)C(NCC34CCCN3CCC4)=C1 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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