NaV1.7 inhibitor-1

Catalog No.: A18933

NaV 1.7 inhibitor

NaV1.7 inhibitor-1

NaV1.7 inhibitor-1 Chemical Structure

CAS NO. 1494585-79-3

NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5.

Availability: In stock

Package Price Qty
1 mg

Regular Price: $320.00

Special Price $256.00

5 mg

Regular Price: $960.00

Special Price $768.00

10 mg

Regular Price: $1,600.00

Special Price $1,280.00

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Biological Activity

NaV1.7 inhibitor-1 is an efficacious voltage-gated sodium channel (NaV) 1.7 inhibitor with an IC50 of 0.6 nM for hNaV1.7, exhibits 80-fold selectivity versus hNaV1.5.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.96 mL 114.8 mL 229.59 mL
0.5 mM 4.59 mL 22.96 mL 45.92 mL
1 mM 2.3 mL 11.48 mL 22.96 mL
5 mM 0.46 mL 2.3 mL 4.59 mL

*The above data is based on the productmolecular weight 435.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18933
Actions Inhibitor
CAS No. 1494585-79-3
Formula C23H30FNO4S
M. Wt 435.55
Purity >98%
SMILES FC1=CC(OCC2(C)CCC3(CC3)CC2)=C(C4CC4)C=C1C(NS(C5CC5)(=O)=O)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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