Biological Activity
NB-598 is a potent competitive inhibitor of squalene epoxidase (SE). NB-598 suppresses triglyceride biosynthesis through the farnesol pathway.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 20.57 mL | 102.85 mL | 205.71 mL |
0.5 mM | 4.11 mL | 20.57 mL | 41.14 mL |
1 mM | 2.06 mL | 10.29 mL | 20.57 mL |
5 mM | 0.41 mL | 2.06 mL | 4.11 mL |
*The above data is based on the productmolecular weight 486.13. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15179 |
---|---|
Actions | Inhibitor |
M. Wt | 486.13 |
Formula | C27H32ClNOS2 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 136719-25-0 |
Synonyms | NB 598 hydrochloride, NB598 hydrochloride |
SMILES | CCN(CC=CC#CC(C)(C)C)CC1=CC(=CC=C1)OCC2=CC(=CS2)C3=CSC=C3.Cl |
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