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Biological Activity
NBMPR is a nucleoside analog that competitively inhibits the equilibrative nucleoside transporter 1 (Kd = 0.1-1.0 nM, IC50s = 4.6 and 3.6 nM in rat and human, respectively).
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.84 mL | 119.22 mL | 238.43 mL |
| 0.5 mM | 4.77 mL | 23.84 mL | 47.69 mL |
| 1 mM | 2.38 mL | 11.92 mL | 23.84 mL |
| 5 mM | 0.48 mL | 2.38 mL | 4.77 mL |
*The above data is based on the productmolecular weight 419.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13701 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 38048-32-7 |
| Formula | C17H17N5O6S |
| M. Wt | 419.41 |
| Purity | >98% |
| Synonyms | NBTI, NBMPR |
| SMILES | C1=CC(=CC=C1CSC2=NC=NC3=C2N=CN3C4C(C(C(O4)CO)O)O)[N+](=O)[O-] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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