NCL1 is a selective inhibitor of Lysine-specific demethylase 1 (LSD1), a pivotal enzyme in the regulation of gene expression through histone modification. With an IC50 value of 2.5 μM for LSD1 and 26 μM for LSD2, NCL1 demonstrates a preferential inhibition of LSD1 over its close homolog. This compound is primarily utilized in research applications related to epigenetics, cancer biology, and neurodegenerative disorders, facilitating investigations into the molecular mechanisms of gene regulation.
NCL1 is a selective inhibitor of Lysine-specific demethylase 1 (LSD1), a pivotal enzyme in the regulation of gene expression through histone modification. With an IC50 value of 2.5 μM for LSD1 and 26 μM for LSD2, NCL1 demonstrates a preferential inhibition of LSD1 over its close homolog. This compound is primarily utilized in research applications related to epigenetics, cancer biology, and neurodegenerative disorders, facilitating investigations into the molecular mechanisms of gene regulation.
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